Isolation and characterization of Samanea SamanFruit Gum: Natural strong binding agent for Controlled drug delivery system

Asha  Parveen; Surendra Pratap Singh; Santosh Kumar R; Pavani M; B.V. Raju M

Asha Parveen Associate Professor, Avanthi Institute of Pharmaceutical Sciences
Surendra Pratap Singh Professor, P.K. University
R. Santosh Kumar Associate Professor GITAM School of Pharmacy
M. Pavani Professor, Avanthi Institute of Pharmaceutical Sciences
M.B.V. Raju Principal & Professor, Avanthi Institute of Pharmaceutical Sciences

Abstract

Controlled drug delivery system (CDDS) is majorly used oral conventional dosage forms. They regulate the drug level in your body for specific time period. This leads to precise medication levels even after taking it once, preventing from taking multiple doses throughout the day. CDDS increases patient compliance and decreases toxicity due to dose dumping in body. In recent era,the number of synthetic and semi synthetic polymers availability in market has increased in order to prepare strong binders for CDDS but they are having many disadvantages such as costly, toxic, there side effects and poor patient compliance along with environmental hazard during synthesis. Because of these side effects we are choosing natural gums such as gum obtained from fruits of Samanea saman which are eco- friendly as well as low cost and strong binder. In the following studies effort were made and depicted of Samanea saman gum extraction from the Samanea saman fruits and the gum is evaluated for their various physical characteristics. Samanea saman possesses various additional properties like non carcinogenicity, broad pH tolerance, high viscosity and biocompatibility. This extract is also used by food and pharmaceutical industries as thickening agent, gelling agent, stabilizer, this fruit constitutes about 65% of polysaccharide in the fruit components.

Keywords: Controlled drug delivery system, Samanea saman, natural gum, Strong binding agent, Polysaccharides, Bioavailability, and Toxicity

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Author Biographies

Asha Parveen, Associate Professor, Avanthi Institute of Pharmaceutical Sciences

Associate Professor, Avanthi Institute of Pharmaceutical Sciences

Surendra Pratap Singh, Professor, P.K. University

Professor, P.K. University

R. Santosh Kumar, Associate Professor GITAM School of Pharmacy

Associate Professor GITAM School of Pharmacy

M. Pavani, Professor, Avanthi Institute of Pharmaceutical Sciences

Professor, Avanthi Institute of Pharmaceutical Sciences

M.B.V. Raju, Principal & Professor, Avanthi Institute of Pharmaceutical Sciences

Principal & Professor, Avanthi Institute of Pharmaceutical Sciences

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