Phytochemical investigation and anthelmintic activity of various leaf extracts of Bixa orellana Linn.

  • Subhashree Padhi Jeypore College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput, Odisha, India.
  • Sangram. K. Panda Jeypore College of Pharmacy, Rondapalli, Jeypore – 764002, Koraput, Odisha, India.


The present investigation was aimed at investing the anthelmintic activity of Bixa orellena Linn. leaves. The dried leaf powder was subjected to successive extraction with ethanol, ethyl acetate, methanol and petroleum ether extract using Indian earthworms Pheretima posthuma as test worm. Various concentrations of each extracts were tested which involved determination of paralysis time and death time of the worm. Albendazole (10mg/ml) was used as a reference standard. The result of the present study indicates that among all the extract, ethanol and methanol showed dose dependant & significant anthelmintic activity. The ethanol extract showed better activity as compared to reference drug albendazole.

Keywords: Bixa orellena, anthelmintic activity, albendazole


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Padhi, S., & Panda, S. K. (2016). Phytochemical investigation and anthelmintic activity of various leaf extracts of Bixa orellana Linn. Journal of Innovations in Applied Pharmaceutical Science (JIAPS), 1(3), 41-45. Retrieved from
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