International Journal of Health Care and Biological Sciences https://saap.org.in/journals/index.php/ijhcbs <p>International Journal of Health Care and Biological Sciences (IJHCBS) is an international online open access, peer-reviewed, quarterly journal Publish Health as well as Life sciences field on the basis of its originality, and serve as a means for scientific information exchange in the international Health Care and Biological science with a strong emphasis on originality and scientific quality. IJHCBS aims to publish quarterly and accepts for publishing original and research articles, review articles, case studies, and reports short communication, meta-analysis.</p> en-US editor@ijhcbs.com (Editor in Chief) editorijhcbs@gmail.com (Support Manager) Tue, 26 Apr 2022 20:03:03 +0530 OJS 3.1.2.4 http://blogs.law.harvard.edu/tech/rss 60 A prospective observational study on drug-drug interactions in chronic kidney disease patients https://saap.org.in/journals/index.php/ijhcbs/article/view/307 <p><strong>Aim: </strong>To review Drug-Drug interactions among CKD patients.</p> <p><strong>Methodology: </strong>A concurrent conciliation study was performed on CKD patients with drug-drug interactions admitted in and around tertiary government and corporate hospitals, Visakhapatnam, Andhra Pradesh, India. Information regarding gender, and variety of drug interactions as mild, moderate, and major were recorded in the standard questionnaire.</p> <p><strong>Result: </strong>Overall 150 prescriptions were included after excluding missing data. The impact of concomitant disease in causing drug-drug interactions in 150 prescriptions them were Hypertension -35%,</p> <p>Diabetes Mellitus-19%, Hyperlipidemia-8%, Asthma- 7%, Seizures- 6%, Thyroid -5%, Congestive Heart Failure- 1%. Total of 201 interactions were revealed of which 15 were major interactions, 139 were moderate interactions, 47 were minor interactions.</p> <p><strong>Conclusion: </strong>By assessing the above data it absolutely was concluded that the patient should possess sound knowledge of drug interactions before employing a selected drug or two or more drugs at the identical time so as to possess identical medication.&nbsp;</p> Rushinaidu T, V. Sri Alekhya S, Bhagya Sri Ch, Harshavardhini R, Rashmitha P, Swetha G Copyright (c) 2022 https://creativecommons.org/licenses/by-nc/4.0 https://saap.org.in/journals/index.php/ijhcbs/article/view/307 Tue, 26 Apr 2022 00:00:00 +0530 Measures of disease frequency and prevalence of drug therapy related problems on basis of prospective observational study in rural hospitalization patients in Nellore https://saap.org.in/journals/index.php/ijhcbs/article/view/330 <p><strong>Aim and objectives:</strong> The study is aimed to assess the frequency and prevalence of drug therapy related problems in patients after hospitalization in Jayabharath Hospital, Nellore. <strong>Specific objectives:</strong> To estimate the opportunities for pharmacist to provide pharmaceutical care. A probabilistic convenient sampling was done to estimate the frequency and prevalence of drug therapy related problems, patients those who are aged above 18 years of either sex were included. Pregnant patients, and those who are having a unwillingness to participate in study were excluded. <strong>Methodology:</strong> This cross sectional study was conducted between March 2022 to June 2022 on patients who discharged to home from Jayabharath Hospital, Nellore. Most of our study population were within the age group of 30 to 45years (33.33 %) followed by 60 to 75years (25.00 %).among the present study population most of them were married (83.3 %) and illiterates (62.5 <strong>%). Results and Discussion:</strong> Nearly 50 drugs are responsible for drug related problems in the present study among those Phenytoin was found to be leading drug in relation to development of drug therapy related problems, Where as Nifedipine was found to be least problem producing drug in present study population. <strong>Conclusion:</strong> Overall we found various kinds of drug therapy related problems, which implies there is a need of continuity of care even after discharge from the hospital.</p> Sushma A., Venkata Suseela Ch, Hepsi B, Mujib Ahmed P, Venkata Reddy S, Kiran kumar C, Venkatesh P Copyright (c) 2022 https://creativecommons.org/licenses/by-nc/4.0 https://saap.org.in/journals/index.php/ijhcbs/article/view/330 Mon, 27 Jun 2022 00:00:00 +0530 Phytopharmaceutical and pharmacological aspects of “pongamia pinnata”-a comprehensive review https://saap.org.in/journals/index.php/ijhcbs/article/view/325 <p>In the last few decades the importance of medicinal plant and its vitality in modern medicine has played a pivotal role in drug discovery and its development. The vast novelty, efficacy and least side effects of the plants have gained the attraction of the researchers, which has led to the exploitation of many traditional medicinal plants and herbs for their therapeutical activities. Even through these efforts there are still some traditional plants that are yet to be exploited for their therapeutic significance, one of such prominent plants is <em>Pongamia pinnata. </em>The plant shows diverse pharmacological activities due to presence of many primary and secondary metabolites. This diversity of many phytoconstituents like alkaloids, flavonoids, tannins, glycosides and other which may be the reason for its pharmacological activities which include wound healing, anti-inflammatory, antibacterial, anti-ulcer, anti-filarial, anti-diabetic and other activities. The present study is an effort to compile all the available details regarding the characteristics of the plant species, phytoconstituents, traditional use, pharmacological uses and research undertaken related to <em>P. pinnata</em>.</p> Harsha T L, Tejaswini K S, Nischith S S, Rupesh Kumar M M, Bharathi D R, Syed Sagheer Ahmed Copyright (c) 2022 https://creativecommons.org/licenses/by-nc/4.0 https://saap.org.in/journals/index.php/ijhcbs/article/view/325 Mon, 06 Jun 2022 00:00:00 +0530