https://saap.org.in/journals/index.php/ijhcbs/issue/feed 2024-04-09T08:00:03+0530 Editor in Chief editor@ijhcbs.com Open Journal Systems <p>International Journal of Health Care and Biological Sciences (IJHCBS) is an international online open access, peer-reviewed, quarterly journal Publish Health as well as Life sciences field on the basis of its originality, and serve as a means for scientific information exchange in the international Health Care and Biological science with a strong emphasis on originality and scientific quality. IJHCBS aims to publish quarterly and accepts for publishing original and research articles, review articles, case studies, and reports short communication, meta-analysis.</p> https://saap.org.in/journals/index.php/ijhcbs/article/view/569 2024-03-19T00:54:47+0530 Niveditha D neelufarshama@gmail.com Venkata Srikanth T neelufarshama@gmail.com Karimunnisa Begum neelufarshama@gmail.com Swathi Priya K neelufarshama@gmail.com

<p>Cardiovascular diseases also called heart diseases which include a group of disorders of the heart and blood vessels. Cardiovascular diseases (CVDs) are the leading cause of death globally. The study was aimed to explore the effect of statins in cardiovascular diseases- chronic stable angina, acute coronary syndrome and in post PTCA patients by monitoring the lipid profile. The study was conducted in the Cardiology department in the Queen’s NRI Hospital. This is a prospective, non-interventional and observational study and 100 population attending Cardiology OPD &amp; IPD in Queen’s NRI Hospital were recruited into the study with their informed consent. This research reported that the cardiovascular diseases in male with prevalence (63%) out of 100 patients and female with prevalence (37%) out of 100 and the prevalence of CSA is 15%, post PTCA is 21%, and ACS is 64% from a total estimation of the study. By using Paired T test the mean difference, estimated variance, standard error of difference, test statistic, test critical are calculated and the comparison between test statistic and critical value. The test statistic is greater than critical t value the alternate hypothesis is accepted by taking the level of significance α = 0.05 and p value less than 0.05 and there is a significant change in lipid profile parameters by using the statins and hence the study is statistically significant with positive outcome.</p>

2024-03-11T00:00:00+0530 Copyright (c) 2024 https://saap.org.in/journals/index.php/ijhcbs/article/view/574 2024-04-09T08:00:03+0530 Yash Srivastav neelashsrv76@gmail.com Ajeet Singh neelashsrv76@gmail.com Mohd Faijan Mansoori neelashsrv76@gmail.com Kumar Madhaw neelashsrv76@gmail.com

<p>A condition known as hemochromatosis results in excessive iron deposition, which damages several organs. Hemochromatosis affects the liver, pancreas, heart, thyroid, joints, skin, gonads, and pituitary among other organs.Famous diagnostician and teacher Dr. Armand Trosseau published the first medical description of a patient with hemochromatosis in a French pathology paper in 1865.Hemochromatosis is a well-defined illness that can be brought on by mutations in any gene that restricts iron entry into the blood. It is typified by normal iron-driven erythropoiesis and hazardous iron accumulation in parenchymal cells of essential organs. When Feder et al. found in 1996 that a mutation in HFE caused hereditary hemochromatosis, it was a significant discovery for the field of hemochromatosis research.Systemic iron excess of hereditary origin resulting from a hepcidin deficiency, including reduced hepcidin-ferroportin binding activity or production, is known as hemochromatosis. A correct diagnosis of this illness is frequently challenging due to the wide range, lack of specificity, and vagueness of its signs and symptoms. The early warning signs and symptoms include arthralgia, weakness, weight loss, and stomach pain.In this review study, we discuss the pathophysiology, epidemiology, symptoms, and aetiology of hemochromatosis.</p>

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