Phytopharmaceutical and pharmacological aspects of “pongamia pinnata”-a comprehensive review

  • Harsha T L Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B G Nagar, Mandya-571448
  • Tejaswini K S Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B G Nagar, Mandya-571448
  • Nischith S S Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B G Nagar, Mandya-571448
  • Rupesh Kumar M Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B G Nagar, Mandya-571448
  • Bharathi D R Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B G Nagar, Mandya-571448
    manirupeshkumar@yahoo.in
  • Syed Sagheer Ahmed Department of Pharmacology, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B G Nagar, Mandya-571448

Abstract

In the last few decades the importance of medicinal plant and its vitality in modern medicine has played a pivotal role in drug discovery and its development. The vast novelty, efficacy and least side effects of the plants have gained the attraction of the researchers, which has led to the exploitation of many traditional medicinal plants and herbs for their therapeutical activities. Even through these efforts there are still some traditional plants that are yet to be exploited for their therapeutic significance, one of such prominent plants is Pongamia pinnata. The plant shows diverse pharmacological activities due to presence of many primary and secondary metabolites. This diversity of many phytoconstituents like alkaloids, flavonoids, tannins, glycosides and other which may be the reason for its pharmacological activities which include wound healing, anti-inflammatory, antibacterial, anti-ulcer, anti-filarial, anti-diabetic and other activities. The present study is an effort to compile all the available details regarding the characteristics of the plant species, phytoconstituents, traditional use, pharmacological uses and research undertaken related to P. pinnata.

Keywords: medicinal plant, traditional plants, Pongamia pinnata, metabolites, phytoconstituents

Downloads

Download data is not yet available.

References

1. Prajwal S, AFRID S, NISCHITH S, KUMAR MR. Phytochemistry, ethnopharmacology and traditional uses of Alhagi maurorum: An Updated Review. Asian Journal of Plant and Soil Sciences. 2021 Nov 20:221-32.
2. Sarker J, Ali MR, Khan MA, Rahman MM, Hossain AS, Alam AK. The plant Aerva sanguinolenta: A review on traditional uses, phytoconstituents and pharmacological activities. Pharmacognosy Reviews. 2019 Jul 1;13[26]:89.
3. Arote SR, Yeole PG. Pongamia pinnata L: a comprehensive review. Int J Pharm Tech Res. 2010 Oct;2[4]:2283-90.
4. Mukta N, Sreevalli Y. Propagation techniques, evaluation and improvement of the biodiesel plant, Pongamia pinnata [L.] Pierre—a review. Industrial Crops and Products. 2010 Jan 1;31[1]:1-2.
5. Edward F. Gilman. Associate professor, Environmental Horticulture Department; Dennis G Watson, associate Professor, Agricultural Engineering Department, Cooperative Extension Service, Institute of food and agricultural Sciences, university of Florida, Gainesville FL 32611; 2004
6. Sangwan S, Rao DV, Sharma RA. A review on Pongamia pinnata [L.] Pierre: A great versatile leguminous plant. Nature and Science. 2010;8[11]:130-9.
7. RasmitaJena ,Diptirani Rath , Sudhanshu Sekhar Rout , Durga Madhab Kar ,Department of Pharmacology, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar
8. Mukta N, Sreevalli Y. Propagation techniques, evaluation and improvement of the biodiesel plant, Pongamia pinnata [L.] Pierre—a review. Industrial Crops and Products. 2010 Jan 1;31[1]:1-2.
9. F.A. Zich; B.Hyland; T. Whiffen; R.A. Kerrigan. "Pongamia pinnata var. pinnata". Australian Tropical Rainforest Plants [RFK8]. Centre for Plant Biodiversity Research, Australian Government. Retrieved 26 May 2021.
10. Sharma KK, Kotoky J, Kalita JC, Barthakur R. Evaluation of antidermatophytic activity of Ranunculus sceleratus and Pongamia pinnata available in North Eastern Region of India. Asian Pacific Journal of Tropical Biomedicine. 2012 Feb 1;2[2]:S808-11.
11. Arote SR, Yeole PG. Pongamia pinnata L: a comprehensive review. Int J Pharm Tech Res. 2010 Oct;2[4]:2283-90.
12. Kesari V, Das A, Rangan L. Physico-chemical characterization and antimicrobial activity from seed oil of Pongamia pinnata, a potential biofuel crop. Biomass and Bioenergy. 2010 Jan 1;34[1]:108-15.
13. Oommen S, Ved DK, and Krishan R. Tropical Indian Medicinal Plants: Oregon, USA. 2000: 599 p.
14. Al Muqarrabun LM, Ahmat N, Ruzaina SA, Ismail NH, Sahidin I. Medicinal uses, phytochemistry and pharmacology of Pongamia pinnata [L.] Pierre: A review. Journal of Ethnopharmacology. 2013 Nov 25;150[2]:395-420.
15. Sharma S, Meher S, Tiwari SP, Bhadran S. In-vitro Antimicrobial Activity and Phytochemical Analysis of Leaves, Seeds, Bark, Flowers of Pongamia pinnata [Linn. Pierre] Against Human Pathogens. Systematic Reviews in Pharmacy. 2021 Apr 28;12[10]:3403-9.
16. Srinivasan K, Muruganandan S, Lal J, et al. Evaluation of anti-inflammatory activity of Pongamia pinnata leaves in rats. J Ethnopharmacol. 2001;78[2- 3]:151‒157.
17. Smitha GN, Asif AK, Mukesh SS, et al. Anti-inflammatory activity of Pongamia pinnata stem bark in rats. J Pharm Res. 2010;3[4]:828‒830.
18. Wadher K, Dabre S, Gaidhane A, Trivedi S, Umekar M. Evaluation of antipsoriatic activity of gel containing Pongamia pinnata extract on Imiquimod-induced psoriasis. Clinical Phytoscience. 2021 Dec;7[1]:1-6.
19. Mahapatra S, Mohanty R, Dehury L, Kumari MM, Mohanty I, Mishra I, Panigrahi G. Evaluate the anti-Anxiety, anti-convulsant and CNS depressant activities of ethanolic extracts of leaves of Pongamia pinnata. Research Journal of Pharmacy and Life Sciences: Volume. 2020 Sep;1[3]:98-108.
20. Punitha R, Vasudevan K, Manoharan S. Effect of Pongamia pinnata flowers on blood glucose and oxidative stress in alloxan induced diabetic rats. Indian J Pharmacol. 2006;38[1]:62‒63.
21. Uddin Q, Parveen N, Khan NU, Singhal KC. Antifilarial potential of the fruits and leaves extracts of Pongamia pinnata on cattle filarial parasite Setaria cervi. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 2003 Nov;17[9]:1104-7.
22. Priya RS, Geetha D, Ramesh PS. Antioxidant activity of chemically synthesized AgNPs and biosynthesized Pongamia pinnata leaf extract mediated AgNPs–A comparative study. Ecotoxicology and environmental safety. 2016 Dec 1;134:308-18
23. Srinivasan K, Muruganandan S, Lal J, Chandra S, Tandan SK, Raviprakash V, Kumar D. Antinociceptive and antipyretic activities of Pongamia pinnata leaves. Phytotherapy Research. 2003 Mar;17[3]:259-64.
24. Rameshthangam PA, Ramasamy P. Antiviral activity of bis [2-methylheptyl] phthalate isolated from Pongamia pinnata leaves against White Spot Syndrome Virus of Penaeus monodon Fabricius. Virus research. 2007 Jun 1;126[1-2]:38-44.
25. Kumar A, Singh IK, Mishra R, Singh A, Ramawat N, Singh A. The Role of Zinc Oxide Nanoparticles in Plants: A Critical Appraisal. In Nanomaterial Biointeractions at the Cellular, Organismal and System Levels 2021 [pp. 249-267]. Springer, Cham.
26. Brijesh S, Daswani PG, Tetali P, Rojatkar SR, Antia NH, Birdi TJ. Studies on Pongamia pinnata [L.] Pierre leaves: understanding the mechanism [s] of action in infectious diarrhea. Journal of Zhejiang University Science B. 2006 Aug;7[8]:665-74.
27. Badole SL, Chaudhari SM, Jangam GB, et al. Cardioprotective Activity of Pongamia pinnata in Streptozotocin-Nicotinamide Induced Diabetic Rats. Biomed Res Int. 2015;2015:403291
28. Dwivedi D, Dwivedi M, Malviya S, Singh V. Evaluation of wound healing, anti-microbial and antioxidant potential of Pongamia pinnata in wistar rats. Journal of traditional and complementary medicine. 2017 Jan 1;7[1]:79-85.
29. Ramdhave AS, Badole SL, Bodhankar SL. Anticonvulsant activity of stem bark of Pongamia pinnata. Biomedicine & Aging Pathology. 2011 Jul 1;1[3]:147-57.
30. Swamy AV, Patel NL, Gadad PC, Koti BC, Patel UM, Thippeswamy AH, Manjula DV. Neuroprotective activity of Pongamia pinnata in monosodium glutamate-induced neurotoxicity in rats. Indian journal of pharmaceutical sciences. 2013 Nov;75(6):657.
31. Karmakar B, Samanta S, Halder G. Delonix regia heterogeneous catalyzed two-step biodiesel production from Pongamia pinnata oil using methanol and 2-propanol. Journal of Cleaner Production. 2020 May 10;255:120313.
32. Kumar R, Ranjith S, Balu H, Bharathi DR, Chandan K, Ahmed SS. Role of nanotechnology in biomedical applications: an updated review. UPI Journal of Pharmaceutical, Medical and Health Sciences. 2022 May 22:39-43.
Published
06/06/2022
Statistics
55 Views | 32 Downloads
Citatons
How to Cite
L, H. T., T. K. S, N. S. S, R. K. M. M, B. D. R, and S. S. Ahmed. “Phytopharmaceutical and Pharmacological Aspects of ‘pongamia pinnata’-a Comprehensive Review ”. International Journal of Health Care and Biological Sciences, Vol. 3, no. 2, June 2022, pp. 38-44, doi:10.46795/ijhcbs.v3i2.325.
Section
Review Articles