Prevention and cure of dermatology disorders using herbal medications: summary

  • Aditya Srivastav Azad Institute of Pharmacy & Research, Lucknow, U.P, India
  • Yash Srivastav Azad Institute of Pharmacy & Research, Lucknow, U.P, India
  • Abdul Hameed Azad Institute of Pharmacy & Research, Lucknow, U.P, India
  • Mohd. Imtiyaz Ahmad Azad Institute of Pharmacy & Research, Lucknow, U.P, India


The use of isolated plant components and herbal extracts in the treatment of wounds and skin conditions is growing. In recent years, numerous new herbal medications, pharmaceuticals, and cosmetics have been produced to address a variety of skin disorders. We concentrate on herbal medications that underwent testing in well-controlled clinical trials or reliable preclinical investigations in this systematic review. Herbal biomedicines are designed to treat a variety of conditions, including atopic dermatitis (using St. John's wort, licorice, tormentil, bitter substances, and evening primrose), psoriasis (using araroba tree, lace flower, barberry bark, indigo, turmeric, olibanum, and St. John's wort), actinic keratosis (using birch bark and petty spurge), herpes simplex (using lemon balm, sage, and rhubarb), rosacea (using green tea, licorice, tormentil, and acne vulgaris) and acne vulgaris (using tea tree oil, green tea, and hop), or to enhance photoprotection (using green tea, Dyer's weed, cocoa tree, carotinoids, and licorice), aesthetic dermatology (using licorice, pine bark, and gotu kola), and wound healing (using birch bark and onion).

Keywords: Skin disorders, Herbal medications, Treatments


Download data is not yet available.


Hay R, Bendeck SE, Chen S, et al. Skin Diseases. In: Jamison DT, Breman JG, Measham AR, et al., editors. Disease Control Priorities in Developing Countries. 2nd edition. Washington (DC): The International Bank for Reconstruction and Development / The Worl. Vasc Embolotherapy. 2006;(Dc):107–18.
2. Joseph N, Kumar G, Nelliyanil M. Skin diseases and conditions among students of a medical college in southern India. Indian Dermatol Online J. 2014;5(1):19.
3. Yousef H, Alhajj M, Sharma S. Anatomy, Skin (Integument), Epidermis. [Updated 2022 Nov 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: 2024;470464.
4. Lopez-Ojeda W, Pandey A, Alhajj M, et al. Anatomy, Skin (Integument) [Updated 2022 Oct 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: 2024;441980.
5. Alkilani AZ, McCrudden MTC, Donnelly RF. Transdermal drug delivery: Innovative pharmaceutical developments based on disruption of the barrier properties of the stratum corneum. Pharmaceutics. 2015;7(4):438–70.
6. Rabiei M, Kashanian S, Samavati SS, Jamasb S, McInnes SJP. Nanomaterial and advanced technologies in transdermal drug delivery. J Drug Target [Internet]. 2020;28(4):356–67. Available from:
7. Tabassum N, Hamdani M. Plants used to treat skin diseases. Pharmacogn Rev. 2014;8(15):52–60.
8. Nair PA, Patel BC. Herpes Zoster. [Updated 2023 Sep 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: 2024;441824.
9. Lei V, Petty AJ, Atwater AR, Wolfe SA, MacLeod AS. Skin Viral Infections: Host Antiviral Innate Immunity and Viral Immune Evasion. Front Immunol. 2020;11(November).
10. Aly R. Microbial Infections of Skin and Nails. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 98. Available from: 1996;8301.
11. Moskaluk AE, VandeWoude S. Current Topics in Dermatophyte Classification and Clinical Diagnosis. Pathogens. 2022;11(9).
12. Thawabteh AM, Jibreen A, Karaman D, Thawabteh A, Karaman R. Skin Pigmentation Types, Causes and Treatment—A Review. Molecules. 2023;28(12).
13. Brenner M, Hearing JV. The protective role of melanin against UV. Photochem Photobiol. 2008;84(3):539–49.
14. Cooper GM. The Cell: A Molecular Approach. 2nd edition. Sunderland (MA): Sinauer Associates; 2000. The Development and Causes of Cancer. Available from: 2000;9963.
15. Elgart ML. Scabies: diagnosis and treatment. Dermatology Nurs / Dermatology Nurses" Assoc. 1993;5(6):464–7.
16. Mahmoud B, Hamzavi I. Overview of vitiligo. Handb Vitiligo Basic Sci Clin Manag. 2016;1–1.
17. Durai PCT, Nair DG. Acne vulgaris and quality of life among young adults in South India. Indian J Dermatol. 2015;60(1):33–40.
18. Sandean DP, Winters R. Spider Veins. [Updated 2023 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: 2024;563218.
19. Ahuja A, Gupta J, Gupta R. Miracles of Herbal Phytomedicines in Treatment of Skin Disorders: Natural Healthcare Perspective. Infect Disord - Drug Targets. 2020;21(3):328–38.
20. Gabros S, Nessel TA, Zito PM. Topical Corticosteroids. [Updated 2023 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: 2024;532940.
21. Gupta AK, Foley KA. Antifungal treatment for pityriasis versicolor. J Fungi. 2015;1(1):13–29.
22. Caramori G, Mumby S, Girbino G, Chung KF, Adcock IM. Corticosteroids. 2019;
23. Alzohairy MA. Therapeutics role of azadirachta indica (Neem) and their active constituents in diseases prevention and treatment. Evidence-based Complement Altern Med. 2016;2016.
24. Hemdan BA, Mostafa A, Elbatanony MM, El-Feky AM, Paunova-Krasteva T, Stoitsova S, et al. Bioactive Azadirachta indica and Melia azedarach leaves extracts with anti-SARS-CoV-2 and antibacterial activities. PLoS One [Internet]. 2023;18(3 March):1–16. Available from:
25. Singab ANB, Mostafa NM, Fawzy IM, Bhatia D, Suryawanshi PT, Kabra A. Herbal Arsenal against Skin Ailments: A Review Supported by In Silico Molecular Docking Studies. Molecules. 2022;27(19):1–38.
26. Pastorino G, Cornara L, Soares S, Rodrigues F, Oliveira MBPP. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phyther Res. 2018;32(12):2323–39.
27. Sharma V, Katiyar A, Agrawal RC. Glycyrrhiza glabra: Chemistry and Pharmacological Activity. Ref Ser Phytochem. 2018;87–100.
28. Alobaidi AH, Hamad ES, Kudair KA, Alsamarai AM. Formulation of Hypopigmentation Cream and Evaluation of its Effect on Skin Pigment. Part I: Formulation of the Product. Our Dermatology Online. 2014;5(1):9–13.
29. Moldovan M, Lahmar A, Bogdan C, Parauan S, Tomuţă I, Crişan M. Formulation and evaluation of a water-in-oil cream containing herbal active ingredients and ferulic acid. Clujul Med. 2017;90(2):212–9.
30. Cohen MM. Tulsi - Ocimum sanctum: A herb for all reasons. J Ayurveda Integr Med. 2014;5(4):251–9.
31. Pattanayak P, Behera P, Das D, Panda S. Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview. Pharmacogn Rev. 2010;4(7):95–105.
32. Hossain S, Urbi Z, Karuniawati H, Mohiuddin RB, Qrimida AM, Allzrag AMM, et al. Andrographis paniculata (Burm. f.) wall. ex nees: An updated review of phytochemistry, antimicrobial pharmacology, and clinical safety and efficacy. Life. 2021;11(4):1–39.
33. Shukla SD, Bhatnagar M, Khurana S. Critical evaluation of ayurvedic plants for stimulating intrinsic antioxidant response. Front Neurosci. 2012;6(JULY):1–12.
34. Sharma R, Martins N, Kuca K, Chaudhary A, Kabra A, Rao MM, et al. Chyawanprash: A traditional indian bioactive health supplement. Biomolecules. 2019;9(5):1–24.
35. Rajeswari R, , M. Umadevi CSR, , S. Selvavenkadesh, K. P. Sampath Kumar DB. Aloe vera: The Miracle Plant Its Medicinal and Traditional Uses in India. J Pharmacogn Phytochem [Internet]. 2012;1(4):118–24. Available from:
36. Sánchez M, González-Burgos E, Iglesias I, Gómez-Serranillos MP. Pharmacological update properties of aloe vera and its major active constituents. Molecules. 2020;25(6):1–37.
37. Kulawik-pióro A, Goździcka WJ. Plant and Herbal Extracts as Ingredients of Topical Agents in the Prevention and Treatment Radiodermatitis: A Systematic Literature Review. Cosmetics. 2022;9(3).
38. Koul B, Pudhuvai B, Sharma C, Kumar A, Sharma V, Yadav D, et al. Carica papaya L.: A Tropical Fruit with Benefits beyond the Tropics. Diversity. 2022;14(8).
39. Lidiani F. Santana 1 ACI 1, , Bruna Larissa Spontoni do Espirito Santo 1, Wander F. O. Filiú 2, Arnildo Pott 3 FMA 3, , Rita de Cássia A. Guimarães 1, Karine de Cássia Freitas 1 * and Priscila A. Hiane 1, 1. Nutraceutical Potential of Carica papaya in Metabolic Syndrome. Nutrients. 2014;59(3):267–86.
40. Salim MN, Masyitha D, Harris A, Balqis U, Iskandar CD, Hambal M, et al. Anti-inflammatory activity of Jatropha curcas Linn. latex in cream formulation on CD68 expression in mice skin wound. Vet World. 2018;11(2):99–103.
41. Oskoueian E, Abdullah N, Ahmad S, Saad WZ, Omar AR, Ho YW. Bioactive compounds and biological activities of Jatropha curcas L. kernel meal extract. Int J Mol Sci. 2011;12(9):5955–70.
42. Benzie IFF, Wachtel-Galor S. Biomolecular and clinical aspects 2nd edition. In: Bode AM, Dong Z, editors. The Amazing and Mighty Ginger. chapter 7 the amazing and mighty ginger; CRC Press/Taylor & Francis. Herb Med. 2011;(ISBN 9781439807132.):92775.
43. Mao QQ, Xu XY, Cao SY, Gan RY, Corke H, Beta T, et al. Bioactive compounds and bioactivities of ginger (zingiber officinale roscoe). Foods. 2019;8(6):1–21.
44. Zhou L, Li J, Kong Q, Luo S, Wang J, Feng S, et al. Chemical composition, antioxidant, antimicrobial, and phytotoxic potential of Eucalyptus grandis × E. urophylla leaves essential oils. Molecules. 2021;26(5).
45. Kumar S, Malhotra R, Kumar D. Euphorbia hirta: Its chemistry, traditional and medicinal uses, and pharmacological activities. Pharmacogn Rev. 2010;4(7):58–61.
46. Kumar S, Malhotra R, Kumar D. IJPhS-72-533. 2010;(August):533–7.
47. Application I. Industrial Application and Health Prospective of Fig ( Ficus carica ) By-Products. 2023;
48. Khan H, Akhtar N, Ali A. Effects of Cream Containing Ficus carica L . Fruit Extract on Skin Parameters : In vivo Evaluation. 2014;(December):560–4.
49. Hong MY, Lumibao J, Mistry P, Saleh R, Hoh E. Fish Oil Contaminated with Persistent Organic Pollutants Reduces Antioxidant Capacity and Induces Oxidative Stress without Affecting Its Capacity to Lower Lipid Concentrations and Systemic Inflammation in Rats 1 – 3. 2015;939–44.
50. Khan WA, Chun-mei H, Khan N, Iqbal A, Lyu S wu, Shah F. Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids. 2017;2017.
51. Amirah N, Zaid M, Gan SH, Lum PT, Najihah N, Mat I. Promising Natural Products in New Drug Design , Development , and Therapy for Skin Disorders : An Overview of Scientific Evidence and Understanding Their Mechanism of Action. 2022;(August 2021).
52. Chakraborty AJ, Uddin TM, Zidan BMRM, Mitra S, Das R, Nainu F, et al. Allium cepa : A Treasure of Bioactive Phytochemicals with Prospective Health Benefits. 2022;2022.
53. Kianian F, Marefati N, Boskabady M, Zahra S. Pharmacological Properties of Allium cepa , Preclinical and Clinical Evidences ; A Review. 2021;20(March 2020):107–34.
54. Coyago-cruz E, Moya M, Gabriela M, Villac M, Rojas-silva P, Corell M, et al. Exploring Plants with Flowers : From Therapeutic Nutritional Benefits to Innovative Sustainable Uses. 2023;
55. Omar SH. Organosulfur compounds and possible mechanism of garlic in cancer. Saudi Pharm J [Internet]. 2010;18(1):51–8. Available from:
56. Khataibeh MH, Abu-samak M, Banu N. Biochemical Investigation of the Effect of Garlic ( Allium sativum ) on 7 , 12- dimethylbenz [ a ] anthracene ( DMBA ) Induced Mammary Cancer in Female Albino Rats. 2006;(March).
57. Babarykin D, Smirnova G, Pundinsh I, Vasiljeva S, Krumina G, Agejchenko V. Red Beet ( Beta vulgaris ) Impact on Human Health. 2019;61–79.
58. Resistance S. A Review of the Role of Green Tea ( Camellia sinensis ) in Antiphotoaging, Stress Resistance, Neuroprotection, and Autophagy. 2019;
59. Chacko SM, Thambi PT, Kuttan R, Nishigaki I. Beneficial effects of green tea : A literature review. 2010;1–9.
60. Hosseinzadeh H, Noraei NB. Anxiolytic and Hypnotic Effect of Crocus sativus Aqueous Extract and its Constituents , Crocin and Safranal , in Mice. 2009;774(January):768–74.
61. Herbal versus synthetic drugs; beliefs and facts Ali Karimi1 , Maedeh Majlesi2, Mahmoud Rafieian-Kopaei1* 1Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran 2Faculty of Nursery and Midwifery, Iran University of Me. 2015;4(1):27–30.
113 Views | 34 Downloads
How to Cite
A. Srivastav, Y. Srivastav, A. Hameed, and M. I. Ahmad, “Prevention and cure of dermatology disorders using herbal medications: summary”, Int J Indig Herb Drug, vol. 9, no. 1, pp. 1-14, Feb. 2024.
Review Articles